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| THVIR12 |
FLASH Radiation Therapy: Accelerator Aspects |
71 |
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- A. Patriarca, L. De Marzi, V. Favaudon, S.J. Meyroneinc
Institut Curie - Centre de Protonthérapie d’Orsay, Orsay, France
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One of the new paradigms in radiation therapy (RT) is the FLASH dose delivery irradiation technique. The FLASH methodology consists in delivering millisecond pulses of radiation (total beam-on time < 100-500 ms) delivered at a high mean dose-rate (> 40-100 Gy/s) and pulse amplitude (> 1E6 Gy/s), over 2000 times faster than in conventional RT. New accelerator ideas are under development or are being tested to deliver this type of beam. In this paper we will report the accelerator technology used for the pre-clinical studies and the necessary developments to deliver this novel dose RT technique.
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| DOI • |
reference for this paper
※ https://doi.org/10.18429/JACoW-IPAC2020-THVIR12
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| About • |
paper received ※ 01 June 2020 paper accepted ※ 12 June 2020 issue date ※ 28 September 2020 |
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| THVIR13 |
CERN-MEDICIS: A Unique Facility for the Production of Non-Conventional Radionuclides for the Medical Research |
75 |
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- C. Duchemin, E. Barbero-Soto, A.P. Bernardes, R. Catherall, E. Chevallay, A. Dorsival, V.N. Fedosseev, P. Fernier, S.S. Gilardoni, J.L. Grenard, L. Lambert, G. Lilli, G. Lilli, G. Lunghi, B.A. Marsh, Y. Martinez Palenzuela, S. Marzari, F. Pozzi, J. Riegert, S. Rothe, T. Stora, J. Vollaire, N.-T. Vuong, S. Wilkins
CERN, Meyrin, Switzerland
- T.E. Cocolios, R. Heinke
KU Leuven, Leuven, Belgium
- F. Haddad
Cyclotron ARRONAX, Saint-Herblain, France
- M.A. Khan
PINSTECH, Islamabad, Pakistan
- N. Michel
SUBATECH, Nantes, France
- J.P. Ramos
SCK•CEN, Mol, Belgium
- Z. Talip, N.P. van der Meulen
PSI, Villigen PSI, Switzerland
- K. Wendt
Johannes Gutenberg University Mainz, Institut für Physik, Mainz, Germany
- K. Wendt
Mainz University, Mainz, Germany
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The MEDICIS facility is a unique facility located at CERN dedicated to the production of non-conventional radionuclides for research and development in imaging, diagnostics and radiation therapy. It exploits in a Class A work sector, a dedicated isotope separator beam line, a target irradiation station at the 1.4 GeV Proton Synchroton Booster (PSB) and receives activated targets from external institutes during CERN Long Shut-Downs. The target is heated up at high temperatures to allow for the diffusion and effusion of the atoms out of the target that are subsequently ionized. The ions are accelerated and sent through an off-line mass separator. The radionuclide of interest is extracted through mass separation and implanted into a thin metallic collection foil. After collection, the batch is prepared to be dispatched to a research center. In the near-future, the radiochemistry process will also be performed in MEDICIS. Since its commissioning in December 2017, the facility has provided novel radionuclides such as Tb-149, Tb-155, Tm-165, Er-169 and Yb-175 with high specific activity, some for the first time, to European research institutes part of the collaboration.
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| DOI • |
reference for this paper
※ https://doi.org/10.18429/JACoW-IPAC2020-THVIR13
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|
| About • |
paper received ※ 09 June 2020 paper accepted ※ 12 June 2020 issue date ※ 23 September 2020 |
|
| Export • |
reference for this paper using
※ BibTeX,
※ LaTeX,
※ Text/Word,
※ RIS,
※ EndNote (xml)
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